Updated: Aug 10, 2022
I've found that every cannabinoid I’ve tried has unique properties that make it stand out from the rest, yet I’ve written off D8THCP as “just weaker” than D9 THCP without actually having tried it. I see a lot of the same sentiment around, so I figured I’d get both and put it to the test.
The folks over at www.voluntate.shop send these both over to me so I could get to the bottom of this for you, so a big shout out to them. They are a very new vendor, so they are to be treated with caution, but and their THC-P is sourced from MC. As I have only tried their THCP, it’s all I can recommend at the moment, but please let me know if you’d like to see a review on more of their products in my “new vendors” series.
First, I’m going to give a quick breakdown of what the different cannabinoid receptors do CB1 is mostly expressed in the brain, adipocytes (fat cells), hepatocytes (liver cells), and musculoskeletal tissues. Cannabinoid Receptor 2 (CB2) is associated with anti-inflammatory and immunomodulatory effects but no psychoactive effects. For the CB1 receptor Now that we know that, lets talk binding affinity to each of those receptors.
D8 THCP: 22nm D9 THCP: 1.2nm
D8 THCP: (need data, plz contact me if you have this number)
D9 THCP: 62nm
So on paper, D8 THCP should be many times worse than D9 THCP, HOWEVER
That was not my experience.
With D8 THCP, the experience was notably weaker, but not as much so as the numbers might have you expect. For me, it felt around ¾ as strong, and notably different. I was surprised how much I enjoyed it. I’d call it a slightly weaker halfway point between D9 THCP and HHCP. Much more body high than the D9 THCP, as well as it being a much calmer, less speedy, more stoney high. I decided to make a blend with both D8 THCP and D9 THCP, and it is really great. Ultra potent, and it feels a lot more rounded out as an experience than with just d8 thcp.
So here’s the real issue. Cost. D8 THCP in general costs about as much as d9 thcp, and when you see that you can get more power for the same price, you almost always will. I think I might be changing my tune a little though. I think I may actually enjoy d8 THCP more because its just more relaxed. It compliments d9 THCP super well in a blend.
I totally think d8 THCP has been unfairly written off, largely by people who haven’t tried it. Binding affinity isn’t everything folks! If you can afford it, and already have some d9 thcp, I say go for it.